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Based on the mechanism of action of ganaxolone and work in preclinical animal models suggesting improved spatial memory function in an animal model of Angelman Syndrome (393), future investigation looking at the clinical value of this agent in anxiety disorders appears warranted

In-use pens already stored at room temperature may still be safe if the total room-temperature period does not exceed 6 weeks and the temperature stayed below 30C

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Sterility failures in the cleanroom The cleanroom is the heart of any sterile compounding operation